And also:

Winston has obviously never seen a cat before in his life. He looks at her like "What kind of dog IS that?" And then the chase ensues. Isabel is bad-ass and will not be submissive to a dog, so she just hisses, swats, and goes about her business.

Cleo does not particularly like Winston. It will be interesting as they try to sort out who is King (or Queen) of the castle. My money is on Cleo.